Prolonged endotracheal intubation is associated with a number of complications including ventilator associated pneumonia, airway injury, or threat of reintubation. Reintubation is a selected drawback particularly because of the lack to cooperate with peri-extubation maneuvers, and the comparatively excessive sedation requirements. Children who have excessive thirst could have excessive blood sugar levels. In conclusion, several research have steered that prophylactic NIV could cut back the chance of submit-extubation respiratory failure in ICU patients at excessive threat of extubation failure. Further research are needed to elucidate the efficacy of HFNC throughout weaning from prolonged mechanical ventilation in a larger inhabitants to prevent publish-extubation respiratory failure in patients at high risk of extubation failure in the intensive care unit and such a clinical condition the place NIV is just not beneficial. 106 mm Hg), with a purpose to avoid tracheostomy on ICU day 16 the primary weaning try was made. We recommend that the first setting of HFNC movement be the same as the maximum inspiratory movement of the ventilator during strain assist ventilation, and the duration of HFNC be gradually extended together with physiotherapy rehabilitation. It is important, nevertheless, that you just focus on this along with your private physician and first receive acceptable lab checks